Christoph Saal
Director SM Analytics Healthcare
Merck KGaA, Frankfurter Straße 250, 64293 Darmstadt, Germany
Supervisor of ESR8
Background
Education: Study of Chemistry (Technical University Darmstadt), Habilitation in Pharmaceutical Technology (Goethe University Frankfurt)
Career:
- Engineer for nuclear engineering at Siemens, Labhead and Director for Analytics Healthcare at Merck KGaA
- Editor for European Journal of Pharmaceutical Sciences and Journal of Pharmaceutical Sciences
- Expert in diverse expert groups at the European Directorate for the Quality of Medicines
Research Interest: Preformulation for New Chemical Entities, solid-state characterization, structural elucidation and impurity profiling including genotoxic impurities
Selected Publications
S. Paulekuhn, J. Dressman, C. Saal: „Trends in Active Pharmaceutical Ingredient Salt Selection based on Analysis of the Orange Book Database“, J. Med. Chem., 2007, 50(26), 6665-6672.
A. Petereit, C. Saal, “What is the Solubility of my Compound? Assessing Solubility for Pharmaceutical Research and Development Compounds” Am. Pharm. Rev., 2011, 14(5), 68-73.
C. Saal, A. Nair, (Editors), “Solubility in Pharmaceutical Chemistry”, De Gruyter, 2020, ISBN 978-3-11-05413-S
C. Schlesinger, L. Tapmeyer, S.D. Gumbert, M.U. Schmidt, C. Saal, „Absolute configuration of pharmaceutical research compounds by X-ray powder diffraction”, Angew. Chem. Int. Ed. 2018, doi:10.1002/anie.201713168
J. Schlingemann, C. Boucley, S. Hickert, L. Bourasseau, M. Walker, C. Celdran, T. Chemarin, C. Pegues, M. Fritzsche, J. Keitel, A. Goettsche, M. Seegel, S. Leicht, B. Guessregen, P. Reifenberg, S. Wetzel, T. Müller, F. Schooren, T. Schuster, M. Liebhold, A. Kirsch, P. Krueger, C. Saal, B. Mouton, S. Masanes, „Avoiding NDMA Formation in Metformin Pharmaceuticals“, Int. J. Pharm., 2022, 620, 121740, https://doi.org/10.1016/j.ijpharm.2022.121740
