Prof. Annette Bauer-Brandl

University of Southern Denmark

Professor of Pharmaceutics at the University of Southern Denmark, Department of Physics, Chemistry and Pharmacy

Supervisor of ESR1, ESR11 and ESR13

Background

Annette Bauer-Brandl is Professor in Pharmaceutics and Biopharmaceutics at the University of Southern Denmark in Odense. Her research interests cover solid state properties of drug compounds, formulation and processing technology of solid dosage forms especially for poorly soluble drug compounds, and their biopharmaceutical implications. Recently, she has focused on the passive transport of drug compounds through biological and artificial barriers. Her group has developed a novel artificial biomimetic barrier which enables her group to work towards new high throughput methods for prediction of bioavailability of drug formulations. She is the author of more than 200 research papers, short communications, reviews, book chapters and a monograph on tablet manufacturing technology and quality assurance.

As a member of the new ‘InPharma’ ITN she is engaged in establishing a new fully integrated, animal-free, end-to-end modelling approach in oral drug product development.

Selected Publications

  • β-Cyclodextrin-dextran polymers for the solubilization of poorly soluble drugs di Cagno, M., Nielsen, T. T., Larsen, K. L., Kuntsche, J. & Bauer-Brandl, A., 2014, In: International Journal of Pharmaceutics. 468, 1-2, p. 258-263
  • Use of Permeapad® for prediction of buccal absorption: A comparison to in vitro, ex vivo and in vivo method Bibi, H. A., Holm, R. & Bauer-Brandl, A., 2016, In: European Journal of Pharmaceutical Sciences. 93, p. 399-404
  • A novel microdialysis-dissolution/permeation system for testing oral dosage forms: A proof-of-concept study Fong, S. Y. K., Poulsen, J., Brandl, M. & Bauer-Brandl, A., 2016, In: European Journal of Pharmaceutical Sciences. 96, 1, p. 154-163
  • Oral bioavailability enhancement through supersaturation: an update and meta-analysis Fong, S. Y. K., Bauer-Brandl, A. & Brandl, M., 2017, In: Expert Opinion on Drug Delivery. 14, 3, p. 403-426
  • Dynamic dissolution-/permeation-testing of nano- and microparticle formulations of fenofibrate Sironi, D., Rosenberg, J., Bauer-Brandl, A. & Brandl, M., 2017, In: European Journal of Pharmaceutical Sciences. 96, p. 20-27
  • Drug permeability profiling using cell-free permeation tools: Overview and applications Berben, P., Bauer-Brandl, A., Brandl, M., Faller, B., Flaten, G. E., Jacobsen, A-C., Brouwers, J. & Augustijns, P., 2018, In: European Journal of Pharmaceutical Sciences. 119, p. 219-233
  • Oromucosal drug delivery: Trends in in-vitro biopharmaceutical assessment of new chemical entities and formulations Brandl, M. & Bauer-Brandl, A., 1. Feb 2019, In: European Journal of Pharmaceutical Sciences. 128, 1, p. 112-117
  • Exploring impact of supersaturated lipid-based drug delivery systems of celecoxib on in vitro permeation across PermeapadⓇ membrane and in vivo absorption Ilie, A-R., Brandl, M., Bauer-Brandl, A., Jacobsen, A-C., Vertzoni, M., Kuentz, M., Kolakovic, R. & Holm, R., Sep 2020, In: European Journal of Pharmaceutical Sciences. 152, 11 p., 105452.
  • Drug Permeability Profiling Using the Novel Permeapad® 96-Well Plate Jabosen, A-C., Nielsen, S., Brandl, M., Bauer-Brandl, A, May 2020, Pharmaceutical Research Volume 37, 6, pp 9311 May.
  • Dissolution/permeation with PermeaLoop™: Experience and IVIVC exemplified by dipyridamole enabling formulations Eriksen J.B., Messerschid, R., Andersen, M.L., Wada, K., Bauer-Brandl, A., Brandl, M.  Nov 2020,  European Journal of Pharmaceutical Sciences Volume 154, 105532